Cannot process message; no node determined for &2

What causes this issue?

To continue processing, the system requires an active node that is
responsible for the recipient &V2& (type &V3&).

System Response

The sending was terminated.

How to fix this error?

Check the SAPconnect settings. The message can only be sent if there is
an active node for which the address range contains the address &V2&.

Error message extract from SAP system. Copyright SAP SE.