No changes are possible in this system

What causes this issue?

In the current system, authorization roles and user role assignments
cannot be changed.
In Release 4.0 this program only has display functionality.
In Release 4.5 and when using a CUA landscape with global role
assignment, this program cannot assign any roles.

System Response

The application functions are locked, and it is not possible to create
or change authorization roles or to change the assignments of users to
roles. The data sent by the portal can only be displayed.
Cleanup functions are provided for removing data that the portal
incorrectly sent to this system.

How to fix this error?

The system issues an error message and will not allow you to continue with this transaction until the error is resolved.

Procedure for System Administrators

Error message extract from SAP system. Copyright SAP SE.