Could not perform operation because of errors in the page layout

What causes this issue?

The page layout contains serious errors.

System Response

For this reason, the system could not ascertain the navigation target
or create a where-used list.

How to fix this error?

Check the page and correct all the errors reported.
Then call the navigation and where-used list again.

Procedure for System Administrators

The system issues an error message and will not allow you to continue with this transaction until the error is resolved.

Error message extract from SAP system. Copyright SAP SE.