RFC destination of the reference check system does not exist

What causes this issue?

The system issues an error message and will not allow you to continue with this transaction until the error is resolved.

System Response

How to fix this error?

On the initial screen of transaction SCI, you can use the function
"Reference Check System Management" to select an existing RFC des
tination via the input help.

Procedure for System Administrators

Error message extract from SAP system. Copyright SAP SE.